AQA 8461

Biology

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Everything you need to know for Biology

Cell Biology

Paper 1 • Both

Key Facts

  • Last-minute priority: organelle functions and transport definitions.
  • Higher SA:V ratio means faster diffusion.
  • Prokaryotic cells (bacteria) are smaller and lack a nucleus.
  • Specialised cells have adaptations that match their function.

Subtopics

Cell Structure and MicroscopyCell DivisionTransport Across MembranesMicroscopy and Calculations
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Organisation

Paper 1 • Both

Key Facts

  • Tissues form organs, organs form organ systems.
  • Enzymes are biological catalysts with an optimum temperature and pH.
  • The heart has four chambers and valves to keep blood flowing one way.
  • Alveoli are surrounded by capillaries for rapid gas exchange.

Subtopics

Digestive SystemEnzymesCirculatory SystemRespiratory System
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Infection and Response

Paper 1 • Both

Key Facts

  • Antibiotics treat bacterial infections, not viral infections.
  • Monoclonal antibodies can target specific antigens.
  • Overuse of antibiotics increases resistant bacteria.
  • White blood cells include phagocytes and lymphocytes.

Subtopics

Pathogens and DiseaseHuman Defence SystemsImmune Response and VaccinationPlant Disease and Defences
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Bioenergetics

Paper 1 • Both

Key Facts

  • Chlorophyll absorbs light for photosynthesis.
  • Respiration happens in mitochondria.
  • Light intensity is the limiting factor at low light.
  • Anaerobic respiration in yeast produces ethanol and carbon dioxide.

Subtopics

PhotosynthesisRespirationRates and Practical Skills
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Homeostasis and Response

Paper 2 • Both

Key Facts

  • Homeostasis keeps internal conditions stable.
  • Thermoregulation uses sweating, shivering, and blood flow changes.
  • ADH release increases when the body is dehydrated.
  • Auxin moves to the shaded side of a shoot.

Subtopics

Nervous SystemHormonal ControlKidneys and OsmoregulationPlant Hormones and Tropisms
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Inheritance, Variation, and Evolution

Paper 2 • Both

Key Facts

  • Genotype is the genetic makeup; phenotype is the expressed characteristic.
  • A dominant allele is expressed even with one copy.
  • Homozygous means two identical alleles; heterozygous means two different alleles.
  • Sex is determined by XX and XY chromosomes.

Subtopics

DNA and GenesInheritance and Punnett SquaresNatural SelectionSelective Breeding
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Ecology

Paper 2 • Both

Key Facts

  • Biodiversity is higher in stable, undisturbed ecosystems.
  • Human impacts include pollution, deforestation, and climate change.
  • Quadrats can be used to estimate population size.
  • Indicator species show pollution levels.

Subtopics

Ecosystems and Food WebsCycles and ResourcesSampling and DistributionDecay and Cycling
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